Tripeptide for Hair – Iles Formula


Key Takeaways: 

  • Fortify Hair: Biotinoyl Tripeptide-1, known as Procapil, strengthens hair at the follicle level, leading to reduced hair loss and improved hair density.
  • Science-Backed: Clinical studies have demonstrated that Biotinoyl Tripeptide-1 not only promotes hair growth but also improves the quality and resilience of hair.
  • Use Over Time: Consistent application and scalp massage with Biotinoyl Tripeptide-1 infused products can enhance blood flow and nutrient absorption, contributing to healthier hair growth over time.


Hair loss and thinning hair are widespread issues that impact both men and women, often leading to decreased confidence and self-esteem. In the search for effective treatments, the hair care industry has turned to scientific discoveries for solutions. 

One such breakthrough is the development of Biotinoyl Tripeptide-1, known as Procapil, a compound formulated to combine the strengths of biotin with the rejuvenating properties of peptides. See the Iles Formula Scalp + Hair Rejuvenating Booster 

This ingredient has quickly gained attention for its potential to fortify hair and encourage growth. This journal focuses on exploring the scientifically-backed benefits of Procapil / Biotinoyl Tripeptide-1 and how it can contribute to healthier, more resilient hair.

Iles Formula prioritizes the harmony between science and simplicity, delivering results that speak volumes through their customers’ radiant tresses. 


A Word From Wendy 

The Iles Formula Scalp + Hair Rejuvenating Booster was formulated using sustainable, antioxidant-rich ingredients to reduce the signs of hair loss + boost growth of thicker + stronger hair. This proprietary, botanically derived blend features more specifically:

  • Biotinoyl Tripeptide-1, known as Procapil 
  • Wasabi – This extract stimulates the dermal papilla cells to better develop hair follicles
  • Tomato + Apple Extracts – Aids cell rejuvenation + reduces aging of the scalp + hair
  • Biotin + 3 Amino Acids – These residues stimulate collagen synthesis 

Did You Know? Procapil is actually derived from plant-based ingredients like olive leaves. 

For more, please see our Oprah Daily Beauty O-Wards winning product: The Iles Formula Scalp + Hair Rejuvenating Booster



Understanding Biotinoyl Tripeptide-1

The Power of Biotin

Biotin is an essential vitamin that plays a critical role in the health of hair by aiding in fatty acid synthesis and energy metabolism. It’s a well-known supplement among those looking to improve their hair’s thickness and growth. 

As an integral component of the natural hair production process, biotin helps in the formation of keratin, giving hair its strength and structure. 

Deficiency in this vitamin can lead to brittle hair and increased hair loss, indicating its importance in hair care. Biotin’s inclusion in Biotinoyl Tripeptide-1 ensures that the hair’s keratin infrastructure is being addressed.


Tripeptide Structure

Tripeptides are a form of peptide specifically designed to penetrate the skin and hair more efficiently due to their small molecular size. This allows them to deliver targeted treatment to the hair follicles, potentially yielding faster and more noticeable results. In addition to their penetrative abilities, tripeptides are known to stimulate growth factors and promote collagen and elastin production. 

The amino acids in tripeptides are the building blocks of proteins essential for hair health. The tripeptide in Biotinoyl Tripeptide-1 is carefully selected for its ability to assist in anchoring the hair in its follicle, reducing shedding, and promoting retention.


The Science Behind Biotinoyl Tripeptide-1

While tripeptides are not found in nature as standalone molecules, their building blocks, amino acids, are naturally abundant in various sources. Here’s how tripeptides are formed and where their constituent amino acids are naturally found:

Formation of Tripeptides: Tripeptides are formed through the process of peptide bond formation. This process involves the condensation of two amino acids, with the loss of a water molecule. The resulting molecule is a dipeptide. Further condensation of a third amino acid with the dipeptide leads to the formation of a tripeptide.

Sources of Amino Acids: Amino acids, the building blocks of tripeptides, are found in various natural sources, including:

  • Protein: Protein is the primary source of amino acids in the body and are found in meat, poultry, fish, eggs, dairy products, legumes, nuts, and seeds.
  • Fruits and Vegetables: These provide a variety of essential amino acids, along with vitamins and minerals crucial for hair health.
  • Nuts and Seeds: These are rich sources of healthy fats and protein, along with essential amino acids like arginine, lysine, and methionine.
  • Grains: Whole grains like brown rice, quinoa, and oats offer a good source of complex carbohydrates and essential amino acids.

While tripeptides themselves are not found directly in nature, understanding the natural sources of their constituent amino acids helps us ensure a diet rich in building blocks for healthy hair growth.


Biotinoyl Tripeptide-1 Benefits for Hair Growth

Strengthening Hair Follicles

One of the primary benefits of Biotinoyl Tripeptide-1 is its ability to bond with hair proteins, thereby reinforcing the follicle and minimizing hair loss. It engages with the keratin in the hair to create a protective layer that can reduce damage from environmental stressors. By enhancing the follicle’s structural integrity, Biotinoyl Tripeptide-1 helps prevent premature hair loss during the hair growth cycle. 

This action can be particularly beneficial during the anagen phase, where the ingredient encourages the retention and growth of hair. 

Over time, the consistent use of this tripeptide can lead to visibly healthier hair emerging from stronger, more resilient follicles.


Ready to Transform Your Hair?

Unlock the secret to fuller, stronger hair with Iles Formula:

  • ✨ Revolutionary Ingredient: Experience the benefits of Procapil, a powerful ingredient that promotes hair growth and reduces hair loss.
  • 🌿 Tailored Excellence: Choose from our Procapil-infused product, meticulously formulated for all hair types and concerns.
  • 👀 Visible Results: Join our community of satisfied customers who have witnessed remarkable improvements in hair density and health.

Don’t wait for change. Create it with Iles Formula.

Try the Oprah Daily Beauty O-Awards winning product – The Iles Formula Scalp + Hair Rejuvenating Booster! Pair along with the Iles Formula Signature Collection for the full impact of the Iles DNA. 



Promoting Hair Density and Fullness

For those struggling with hair thinning, Biotinoyl Tripeptide-1 can make a significant difference by improving the thickness of each hair strand. The ingredient’s action at the follicular level helps increase the proliferation of hair cells, leading to a denser, fuller head of hair. By promoting a prolonged anagen phase, the hair growth process is extended, allowing hair to grow thicker and more voluminous over time. 

This tripeptide also helps to reduce the rate at which hair sheds, maintaining an overall appearance of fullness. As more and more strands remain in the growth phase, the cumulative effect is a noticeable increase in both hair density and scalp coverage.


Enhancing Scalp Health

A nourished and well-cared-for scalp is the foundation for healthy hair growth, which Biotinoyl Tripeptide-1 directly contributes to. Its anti-inflammatory properties may help soothe the scalp, reducing redness and irritation that could otherwise disrupt hair growth. 

Moreover, the tripeptide aids in hydrating the scalp, ensuring that hair follicles are not choked by dryness or flakiness. By promoting better blood circulation in the scalp, Biotinoyl Tripeptide-1 ensures that hair follicles are well supplied with the nutrients necessary for growth. 

Its contribution to a balanced scalp environment prevents issues like dandruff and dermatitis that can hinder hair health.


Understanding The Biological Impact

There are many different tripeptides, each with unique properties and functions. Here are some examples of tripeptides with various benefits:

Hair Growth:

  • Biotinoyl Tripeptide-1 (BT-1): Promotes hair growth, increases blood circulation to the scalp, and extends the anagen phase.
  • Copper Tripeptide-1 (GHK-Cu): Stimulates collagen production and cell regeneration, contributing to healthier hair follicles and improved hair growth.
  • Capixyl™: Reduces hair loss and promotes hair growth by targeting specific cellular mechanisms.



  • Palmitoyl Tripeptide-5 (MATRIXYL™): Stimulates collagen and hyaluronic acid production, leading to reduced wrinkles and improved skin elasticity.
  • Acetyl Hexapeptide-8 (Argireline™): Relaxes facial muscles, preventing the formation of wrinkles and expression lines.
  • Tripeptide-1 (Gly-His-Lys): Protects against collagen breakdown and promotes skin renewal.


Wound Healing:

  • Glycyl-L-Proline-L-Hydroxyproline (GPH): Promotes collagen synthesis and fibroblast proliferation, accelerating the wound healing process.
  • Seryl-Tyrosyl-Serine (STS): Reduces inflammation and promotes tissue regeneration, leading to faster wound healing.
  • Thymosin Beta 4 (TB4): Regulates immune response and stimulates cell proliferation, contributing to wound healing.


Other functions:

  • Glutathione: A powerful antioxidant that protects cells from damage and promotes overall health.
  • Carnitine: Helps convert fat into energy, improving athletic performance and reducing fatigue.
  • Carnosine: Protects against protein glycation, a process associated with aging and various diseases.


Scientific Research on Biotinoyl Tripeptide-1

Clinical Studies

The promising benefits of Biotinoyl Tripeptide-1 are supported by clinical studies that demonstrate its efficacy in promoting healthy hair growth. 

  • Participants in trials have shown noticeable improvements in hair density and anagen-to-telogen ratio, suggesting the compound’s role in enhancing the growth phase of hair.1
  • Researchers have found that Biotinoyl Tripeptide-1 can significantly increase hair’s resistance to traction, lowering the occurrence of hair fall during brushing and styling.2
  • These studies underline the compound’s potential for not only increasing hair growth but also improving hair’s inherent quality. 



A Guide to Using Tripeptide for Hair Growth

Daily Hair Care Routine

For the best of the Iles Formula DNA, start with the Iles Formula Signature Collection which features the:

CLEANSE: Iles Formula Shampoo – For all ages + hair types. Immediately detangles + evens out porosity + adds root volume. 

REPAIR: Iles Formula Conditioner – Excellent on all hair types. Immediately transforms dry, straw-like hair to sumptuous, lustrous texture. Also includes no residue + no bond building + no peptides. 

PROTECT: Iles Formula Finishing Serum – Delivers an organic memory + spun silk suppleness to the hair. This provides protective styling (heated tools + UV + Color Fade + Humidity) and never weighs hair down. 

BOOST: Iles Formula Scalp + Hair Rejuvenating Booster – A powerful leave-in treatment featuring Procapil. Reduces the signs of hair loss + boosts growth of thicker + stronger hair. 


Final Thoughts: Embracing Science for Healthier Hair

When deftly utilized by brands like Iles Formula, Tripeptide becomes a pillar of transformative hair care

With continued scientific research and clinical studies affirming its benefits, Biotinoyl Tripeptide-1 stands out as a key ingredient in the future of hair care. Its impact on the strength, density, and overall vitality of hair makes it a sought-after solution for many facing hair growth challenges. 

Embracing Biotinoyl Tripeptide-1 enriched products could be a transformative step toward achieving the luscious, healthy hair that everyone desires.

As we become more attuned to the needs of our hair and the offerings of science, embracing lines like Iles Formula allows us to foster the health and vitality of our hair. Unlock the full potential of your hair’s growth and beauty with the diligent science of Iles Formula products. 

For more, check out the Iles Formula Bestsellers today!


FAQs on Tripeptide

What are tripeptides?

Tripeptides are short chains of amino acids, the building blocks of proteins. They have three amino acids linked together by peptide bonds. Tripeptides are smaller than proteins and can be absorbed more easily by the skin and scalp.


What are the benefits of tripeptides?

Tripeptides offer a variety of benefits, depending on the specific type of tripeptide. Some of the potential benefits include:

  • Hair growth: Stimulating hair follicles and promoting hair growth.
  • Skin health: Improving skin elasticity, reducing wrinkles, and promoting wound healing.
  • Muscle growth: Building and repairing muscle tissue.
  • Boosting the immune system: Helping the body fight off infection.


Are tripeptides safe?

Tripeptides are generally considered safe for most people. However, it is always a good idea to talk to your doctor before using any new supplement or topical product.


What are the best tripeptides for hair growth?

Some of the most popular tripeptides for hair growth include:

  • Copper tripeptide-1: This tripeptide is thought to stimulate hair growth by increasing blood flow to the scalp and promoting the production of hair follicles.
  • GHK-Cu: This tripeptide is similar to copper tripeptide-1 and may also help to stimulate hair growth.
  • Acetyl hexapeptide-8: This tripeptide is known for its anti-aging properties and may help to prevent hair loss and wrinkles.
  • Matrixyl 3000: This tripeptide is a blend of two other tripeptides and is thought to help to increase collagen production and improve hair density.
  • Tripeptide-21: This tripeptide has anti-inflammatory properties that may help to reduce scalp inflammation and improve hair health.


How long does it take to see results with tripeptides?

It can take several months to see results with tripeptides. Be patient and consistent with your hair care routine.


Where can I find tripeptides in hair products?

Tripeptides can be found in a variety of hair products, including shampoos, conditioners, serums, and masks. Look for products that specifically mention tripeptides on the label.


Are tripeptides better than other hair growth ingredients?

There is no one-size-fits-all answer to this question. Some people may find that tripeptides are more effective than other hair growth ingredients, while others may not see any difference. It is important to try different products and see what works best for you. 


  1. Burg D, Yamamoto M, Namekata M, Haklani J, Koike K, Halasz M. Promotion of anagen, increased hair density and reduction of hair fall in a clinical setting following identification of FGF5-inhibiting compounds via a novel 2-stage process. Clin Cosmet Investig Dermatol. 2017 Feb 27;10:71-85. doi: 10.2147/CCID.S123401. PMID: 28280377; PMCID: PMC5338843.
  2. Pyo HK, Yoo HG, Won CH, Lee SH, Kang YJ, Eun HC, Cho KH, Kim KH. The effect of tripeptide-copper complex on human hair growth in vitro. Arch Pharm Res. 2007 Jul;30(7):834-9. doi: 10.1007/BF02978833. PMID: 17703734.

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